I use BE-86 in my 41 mag for mid to upper mid range loads, it will do anything Unique will do and it meters well, and has a flash suppressant, and burns cleaner than Unique. It also has almost the same burn rate.
I've used BE-86 in every hand gun caliber I load for and honestly don't see any reason to ever go back to Unique.
I work up my own loads when there is data or not so you have to do what your comfortable with.