I have quite a bit of experience with the Ruger Single Six. As a kid, my best friend had one. He carried it, and we shot it a LOT for years.
After getting a job, I bought one. It was blued, and had a 6"+ barrel. I don't recall what happened to it. I do remember that I had rubber grips on it, a Wolf spring kit in it, and had an aftermarket full rib on the barrel.
About 15 years ago I bought another one. It was a 5 1/2" stainless. I shot many, many thousands of rounds out of it and it was at least fourth hand when I got it - one of my friends bought it at a pawn shop.
Within the last year, I sold that one and bought two new ones. One is stainless with a 4"+ barrel. It was a special run of these short barreled guns produced for Lipsey's. I ordered it as soon as I found out about it. When I went to pick it up, there was a blue, 6"+barreled Bisley Single Six in the case. I was so taken by it, that I bought it also.
I have owned those two guns for less than six months and have fired several thousand rounds out of each of them. I couldn't limit myself to one.
I don't believe I have ever fired a single magnum round out of any of them.
I consider the Ruger Single Six to be a must have. They are one of my most frequently fired handguns.