I tried some 75 gr Hornady A-Max in my fast twist .223 meant for 90 gr.
I got one string that was nothing but 10s, Xs, and misses. Scorer said he could see the silver streaks in air as they broke up.
Loaded them down a bit and they shot great at midrange.
I had been losing 90 gr Sierras in flight, too. I fixed that by going to JKL and Berger.