My list has shifted over the years with the introduction of different cartridges in the past 20 years or so.
Starting with the big guys - I like what I read about the 375 Ruger. This would replace rhe 458 win, 416 rem, and 375 h&h. Thanks
@LoonWulf and
@WrongHanded and others for sharing your 375 experience.
The mid sized mag - I'll stick with the 8mm Rem Mag. Craig Boddington's writing about this cartridge has stuck with me.
Someday I will spend the cash on a custom rifle in the cartridge.
The workhorse mag - The 300 wsm is a super choice and covers the 7 & 30 caliber mags. I feel that the recoil is manageable and will cover anything that standard 06 cartridge can plus.
All around cartridge - 308 win the cartridge to start with and stick with. For deer hunters just buy one and fill up the pickup bed with venison.
Reach out and touch it cartridge - 6.5-300 Weatherby. With more and more high BC bullets in 6.5 why not one that goes 3500.
This cartridge would be awesome for antelope and bean field whitetails were a 400 yard shot would be more common.
I didn't leave room for a woods walk deer rifle (as a honorable mention)- I would go with 45/70. This also makes a great camp rifle and hike cartridge in big bear country!
Yes - my 7mm rem mag is not on the list. I think the 300 wsm is a better cartridge.
The 308 win will do 99% of what the 30-06 will do. I still love the 30-06 but would recommend the 308 for its available short action rifles.
The 30-30 will always be my favorite woods rifle but the 45/70 has it hands down in big bear country.