My wife and I both carry a Maxpedition Fatboy with a 5.11 holster. I am very impressed with their quality and the options that are available. At first some people made fun of my "man bag." But I am not one to be overly concerned with the opinions of others. They got used to seeing me with it and haven't heard any comments in quite a while.
Over time I got used to carrying it, and found it SO much more convenient than a holster. Gun, mags, light, knife, multi-tool, notepad, pen, handcuffs, key. And because I am a new father... two diapers, wipes, bottle, plug (pacifier), and formula packets. It's a diaper bag.
If you are concerned about the opinions of others or style (not meant as a bash, just a statement) then it is not really the best way to go. If you are more concerned with utility, durability, and convenience... the Maxpedition packs are pretty hard to beat.
www.lapolicegear.com has them for a good price.
Where I live they don't really scream "gun" either... okay, maybe a little. But I have seen several non-firearm types carrying them. If you read the online reviews you will notice that only about half of the people use them for firearms carry.