It all goes back to how you want to hunt, and how many times you're willing to shoot. People buy these 20,000 dollar Nitro Express doubles to hunt Rhino and Elephant and whatnot. Well, you wanna know what round has killed more elephants than all the others combined? 7.62X39! The AK will drop a big elephant quickly. Just start emptying rounds into the head, until it falls. So, I think that the 10mm could be used to take most N.American game, especially in an autoloader. Shoot it, if it doesen't go down, shoot again.