Tough call since you barred the rimfire model (My Ruger Standard) I dearly love.
It would be a toss-up between three.
1. is my .380 Makarov
2. CZ75B in 9mm
3. FN Forty-Nine in .40
The Makarov is just fun. The makawrap grip makes all the difference between fun and masochism...a clear reference to the crumby red plastic things I put on to make it look more correct. It's a commercial Bulgarian and it wears commercial grips. It never fails to go bang either.
The CZ75B, ah yes. The ergonomics, the tame recoil, the accuracy. Whats not to love. The thing I hate is that I can never seem to afford enough ammo to keep myself happy long enough.
The FN Forty-Nine. It's lightweight, its a full size gun and that .40 makes a nice loud bang. Accurate, high capacity, uber-reliable and easly the best ergonomics of any gun I own.
The novel safety system...or lack thereof is always nice. The repeatable secure striker (fancy DAO setup) gives a nice consistent trigger pull that doesn't stack up and allows you to feel the parts inside working.
The trigger is a little heavy at 10lbs, but I'll take a good, consistent 10lbs over a lighter, less consistent pull.