Acknowledging that:
All pistols are machines subject to failure...
All manufacturers let lemons slip through the production line...
Individual examples of almost any design can deliver excellent reliability...
I still believe that there are only a handful of widely used and time-tested semi-auto designs that monotonously deliver on demand (as a design class):
Glock series
1911/A1 (full-sized stock G.I. gun)
BHP/P-35
SIG 2XX series
HK USP/C series
Beretta 92 series (usually)
CZ 75 series
Walther P-38
Makarov
S&W 2d/3d Generation Semi-Autos
Ruger P-series
There are lots of other models and makes out there which are excellent firearms, but these are the ones that come to mind for passing my "Trouble Inside the Next Room Test".
If you had to walk into a room with a new boxed handgun on a table, load the weapon, and walk directly into a possible shootout in a second room...what weapon would you be satisfied to find in that box (without any chance to inspect, disassemble, practice with, or other wise manipulate that handgun). Simply load and go...
My mental winners list includes the above weapons because they all have proven military and/or LEO service records. Hard use guns for hard times. Almost all examples will prove to be dependable bullet launchers the first time you have to use them.
Of these, I think the CZ75 equals or betters all the others in terms of reliability, ergonomics, accuracy, capacity, effective caliber, controllability, and PRICE.
Admittedly, the 1911 comes in .45 and the Mak is cheaper, but all of these weapons can be had in a caliber-change variant (if that's important) and the NIB variants of the Milsurp P-38/Mak aren't really cheap.
Some younger members may not realize that the CZ 75 was a "Grail Gun" back in the late '70s and the 1980s. They were as sought after as Colt Pythons and HK P7s are today. Prices were in the $1200 to $1800 range for rare examples purchased (usually in Canada) and brought into the U.S. This was at a time when most premium handguns (Python, S&W M29, Colt Govt Model, BHP, etc.) were priced from $450-$600 (in 1980's dollars).
Besides being a GREAT semi-auto and delivering quality and performance equal to some wonder-nines costing twice the money (SIG & HK), I simply like the '75 because of looks and feel. It does remind me of my Hi-Power...it's got heft, but with svelte looks...and defies the Teutonic penchant for slapping a box on top of a handle
(and yes, I own those too...).
Oh well...the coffee is cold...enough of this IMHO rambling.