I can't speak to the way it used to be, but as far as today goes, I've heard people say modern bullet technology has shrunk the performance gap between, say, 9mm and .45 (light & fast vs. heavy & slow). And if you want a little bit more of both weight and speed, the .40S&W and the 10mm would cover that as well. (My personal favorite is the 10mm.) But all that was more or less to say that I think lscurrier was right. All the existing pistol calibers are just fine; there's really no need for any more. I think a better question might be, why clutter the sidearm landscape with any more calibers? Just for one example, couldn't the 10mm adequately cover any task that would call for something like a .357Sig?