I can't comment on full-power, and defensive loads, but the cheap stuff in .40 is about $8.50 a box, and in 10mm, the cheap stuff is $15.00 a box, sometimes a little less.
No, the ripoff stuff is $15 a box. The cheap stuff is $8.00-9.50/50 by the case if you order from Georgia Arms.com, and Ammoman.com often has cheap Federal American Eagle ammo in bulk too.
http://www.georgia-arms.com/pistol.htm#ee
What are the differences between 10mm and .40 S&W?
- The 10mm case is longer, has thicker walls, can safely withstand much higher pressures, and uses large pistol primers instead of small pistol primers.
- The SAAMI average peak pressure spec for .40 S&W is 35,000 psi, while it is 37,500 for 10mm Auto.
- A 10mm cartridge with a 180gr bullet loaded has roughly DOUBLE the internal volume for powder that a .40 S&W cartridge loaded with a 180gr bullet has. Hence a .40 S&W load will launch a 180gr bullet at 950 ft/sec, while a 10mm can launch a 180gr bullet over 1,300 ft/sec.
- 10mm can handle heavier bullets and still launch them at respectable speeds; a 10mm can launch a 220gr bullet faster than a .40 S&W can launch a 180gr bullet.
- Because its overall length is shorter and it is considerably less powerful, the .40 S&W can be chambered in physically smaller guns than the 10mm Auto can.
- 10mm practice ammo is more expensive than .40 S&W ammo generally, but not as much as people claim...
if you are smart enough to not buy at the corner store and pay 50% more than you should.