I was a lab tech for a R&D center for 20+ yrs. I always had fun when one of the new phd's prediction was way off. We always had side bets on what would happen when we took a test sample to destruction. Most learned not to wager against me
because all my experience would beat them. One of my orders was to keep them from killing them selves or someone ease. It came closer than I liked one time, evacuated the building for 2 hrs till all the poisonous gas was scrubbed. At least he had enough since to open the valve in a lab designed to handle the gas, fully monitored, and containment. My boss and manager was not very happy with the event. The manager was on a conference call with a VP at the time of the event.
High press is something you really have to be careful with. I worked with gas pressures to 30kpsi, volume of ~ 1 cuft. I was told when they went to design my test bunkers, a catastrophic failure was the equivalent of 5 sticks of TNT going off. The cells were designed not take damage and contain the gas if needed. The best bomb shelter made.
Since gun powder is not linear it makes it harder to predict.