My $0.02...
This is my take...
Glock makes good guns, but they are even better with marketing and brand management. Glocks have marginal ergonomics and are just about the only modern autoloaders that don't fully support the ammo casing with the barrel. All guns can blow up if there is a bad enough ammo malfunction, but Glocks are particularly sensitive to this sort of thing (especially with 40 S&W and .357 sig). A lot of Glock fans get really heated when people point this out, but it is the truth, sorry.
I have no agenda. Heck, I don't even own an autoloader. I prefer revolvers. I have, however, shot a lot of autoloaders and have developed my own preferences. I probably will get around to buying an autoloader, eventually.
I like Glocks, but probably wouldn't be interested in anything outside of their 9 mm line without an after-market barrel for better chamber support.
Glocks are durable (aside from the barrel support issue), they are accurate, they are reliable, they are simple, but they aren't perfect. A balanced view of these firearms is that they are not the paragon of perfect reliability that the internet chatter makes them out to be. I've seen glocks malfunction, and the people didn't need to "torture" the gun to induce the malfunctions. A malfunction is a malfunction. I don't care if someone "limp-wristed" the gun or not. If it doesn't go bang, it was a malfunction. If you get shot because you were delayed clearing a malfunction, I doubt that you'll care if it was "user error". I think that the online torture tests are a bunch of BS. Torture tests sell guns. I laugh every time someone starts to go on and on about these tests. Sorry. I am a skeptic with a marketing MBA and a background in science. I've yet to see an online torture test that was completely unbiased and done in a format that couldn't be fixed. Just because some guy said that he shot 20,000 rounds through a gun without a malfunction doesn't mean that it is true. People lie. People that stand to make a lot of money if they can sell you on something tend to lie more often. I think that Glocks are among the more reliable firearms, but so are Berettas, Sigs, HKs, XDs, M&Ps, CZs, ...
The P250 stumbled a little out of the gate. The Sig faithful don't seem to like it very much on the Sig forum. It seems that many people have reliable P250s, but there have been some teething issues with those guns. I considered buying one a while back, but decided that my next gun purchase would either be a XD45 compact or a M&P. I think that Sig would take care of you, but Sig stumbled with the GSR, the mosquito, the P250, and now with the P238. I don't have as much faith in them as I once did. The P250s are probably fine, now. I just personally wouldn't spend my hard earned money on what appears to be a gamble. Most Sigs are still very expensive, but I question the quality of the more recent "vintages".
For my money, I would probably go with an XD45 if you want a .45. If you want a 9mm or a .40 S&W, I'd recommend the M&P, the XDm, any CZ, or maybe a Beretta (I really like the 90-two). The M&P had some teething issues as well, but those issues have been corrected for a pretty good amount of time.
The newer Sigs have a finish called Nitron. It is a Vapor deposition finish. It is a Tungston Diamond-Like Carbide finish. Plenty tough and plenty rust-resistant. Most new Sigs have stainless slides and this stuff on top. This stuff should hold up pretty well. Glock have a metal treatment called tenifer. Contrary to popular belief, tenifer isn't the black finish. The black finish is placed on top of the tenifer. Glock's black finish isn't nearly as tough as the tenifer. It is probably not even as tough as nitron. Tenifer is similar to melonite and HK's Hostile environment finish. Nitron is a Vapor Deposition finish that is more similiar to Remington's Trinyte finish or Diamond Black (but probably not nearly as tough as either of those).
Out of the guns that you listed, I'd go with the Glock. If you do this, you might want to buy a fully supported after market barrel. The lack of chamber support helps Glocks to feed reliably. I have no experience with doing this, but I would expect that a Glock with an after market barrel may not feed as reliably. It was built to function without the extra support. I like 9 mm Glocks. I don't like Glocks chambered for more powerful cartridges. That is just my opinion.