if she becomes an avid shooter, she can learn to be good with any handgun, except big magnums that overload her stature.
that said, after i forced my wife to burn 1,000 rounds as an entry level training to any new platform she had a fancy for, she got good with all of them. but one day a wise old man at a gun store gave me a genuine pearl of wisdom....
since there is no way to know beforehand if she will take up the habit or not before the first handgun purchase, let ~HER~ pick it with this method:
go to a user friendly store that will not get illiterate about her handling a lot of handguns. explain to them what is transpiring. start with around .380/9mm/38 special as entry level calibers. they represent what many feel to be baseline defensive rounds. have her pick a target on the wall, away from any bystanders. a large clock or similar size is about right. have her look at the target, close her eyes, and then raise the weapon to where she recalled the object being. the one that comes closest to hitting the target when she reopens her eyes is the best first handgun choice for her.
MOST SELF DEFENCE SHOOTINGS HAPPEN AT NIGHT, AND AT BAD BREATH RANGES.
that is why a handgun that is instinctive for her to bring into minute of pie plate up close is a very good idea.
don't have her dry fire it as this may lose the salesman's cooperation. if the smaller caliber presents no problems as to recoil, later on she can fire bigger ones to determine her "flinch threshold", and maybe get a better stopper. if she goes gun crazy in a coupla years, let her pick whatever she wants, she'll GET good with it.
gunnie