Probably the best plan. I use Unique with a 260 grain lead bullet and have been content with the results from my 25-5. I get about 900 fps and yes, it does anchor deer....Having said that..... I'll load them up with my Lee Loader and shoot them in my Model 25 ( with good shot placement they drop deer just like a hot .44 mag... ) at around 800 fps...
Good luck!
Kevin