Regardless of how is does in tissue or gelatin, penetration through barriers would be as much or more than the more sedate loads and muzzle blast would be massive compared to other loads.
You've apparently never had trigger time with DT's 135gn Nosler load.
It's been tested against different intermediate barriers by various users who've posted the results on-line (check 10mm Talk; GT's 10Ring - remember, the "Search" function is your buddy
)
Bottom-line: it consistently exhibits minimal penetrative capability against said barriers or materials, being designed to
fragment, rather than drive deep into the target.
Hence, this load has garnered the on-line moniker,
"Frag Nasty" for its tendency to fragment horrifically. As noted earlier, a COM hit on a BG's upper thoracic cavity would be ... well, ... not pretty.
Certainly not a magic bullet, but it appears to perform within its design parameters.
Moreover, this load's blast and concussive emission is certainly no worse than other high-performance 10mm ammo, while its actual felt-recoil is
less than other DT 10mm loads, due to the projectile's weight. In fact, I've fired this one against other DT & Buffalo Bore loads and out of a stock G20 the felt-recoil was comparatively mild.
Firing this load inside a structure is going to be loud for sure, but so would any major-caliber handgun round, and a shotgun blast would be just as deafening.
Its is possible that due to its high velocity and relatively fragile HP it may fragment when striking a wall or other surface but I wouldn't want to count on that.
Actually, that's exactly what it does - again, based upon reported user experiences.
The OP can certainly choose what he likes, but he shouldn't dismiss this load out of hand without doing more research or, perhaps, getting a box or two and testing it himself.