With the exception of the Yugo M57 Tokarevs just coming on the market, the safety on Tokarevs is just an add-on to satisfy the import requirement. It should not be used as a carry safety, though I find it useful at the range. The Yugo Tok have a 1911-type safety.
If you were to carry the Tok, chamber empty with the hammer cocked would probably be best. If the Tok is set at half cock, it locks the trigger and the slide.