Pick 3 rifle calibers.

[woad_yurt]

.22LR, 7.62X39 & 8MM Mauser.

Yes, yes, I know some of you are asking "why 8MM?" Because I have a ton of it and got it when it was cheap; I've got enough for decades. Went a little overboard buying it up when I got my K98k.... Anyway, it's a great round.

 

[Terrierman]

One always always always needs a good .22 LR bolt rifle first and foremost.

To cover the full spectrum in centerfire:

.223
7mm-08
.375

But one good .30-06 would really take care of everything now, wouldn't it?

 

[RugerOldArmy]

Small:

.223, .22 BR, .22-250, or 6mm BR Norma Accuracy would be key here, and all listed would be good, but 6mm BR has impressed the hell out of me. .22 PPC or 6mm PPC would be contenders if they weren't such a PITA to reload.

Medium:

.308 Win or .270 Win .308 is a fantastic cartridge, but Jack O'Connor knew a good thing when he saw it.

Larger:

.375 H&H or .45-70 Two classics, both winners.

 

[kennyboy]

Small- .223 Remington

Medium- .30-06 Springfield

Large- .338 Lapua Magnum

 

[Pigspitter]

17HMR
.308Win
.300Pegasus

 

[jh9x18ky]

22lr
243
7mm-08/308

 

[Fatkid2008]

.203
.30-06
.30-06

 

[TexAg]

.22lr
6mm
.30-06

 

[EdLaver]

5.56 x 45
7.62 x 39
.308

 

[TnBigBore]

32-20
300 Savage
45-70

 

[lorddal]

22lr
30-06
30-06

 

[casio02478]

22-250
270 Win
338 Win Mag

 

[Gunfighter.45]

5.56 x 45
7.62 x 51
6.5 Grendel

 

[Boris Barowski]

.223 Rem
.308 Win
.338 Lapua Magnum

 

[Chrome]

.17 HMR
.30-06
7mm Mag

Later,
Chrome...

 

[doc2rn]

.22 lr
.223
.308

Easiest pick 3 I ever seen

 

[3pairs12]

.223
.243
.300 ultra mag

 

[sig226]

I wouldn't use your definition of middle and large calibers, so mine would be a little different. I also assume you're not including rimfire in this. A good .22LR is essential.

Small caliber: .223/5.56, AR-15

Medium caliber: .30-06, useful for anything.

Large caliber: .45-70 because I loved my Guide Gun and I want another one in stainless.

 

[TimboKhan]

This is easy. .22, .223 and .30-06

 

[Intrepid Dad]

.223 Rem
.308 Win
.45/70 Govt

 

[Dobe]

I am assuming you are asking for centerfire only. If not, then I would have to slip in a good .22LR somewhere.

.223/5.56 for the domestic issues

.243 for up to and including deer

.308/30-06 for all other shooting and hunting in my area of the world.

 

[azhunter12]

.223
.243
30-06

 

[kir_kenix]

.223
30-06
.375 h&h

 

[marksman13]

22LR, 308 Win and 300 Win Mag. I figure I could do just about anything I wanted with those three.

 

[dr0]

.204 Ruger
.270 Win
.338 WinMag