They're interesting guns. Hornady also has a new personal defense ammo brewed for shorter barrel, and it's penetration and expansion is amazing. Tests can be found on YouTube. These rounds suggest that the PMR-30
might possibly be suitable for self-defense. Home defense when I'm not here was my wife's concern. And even if she misses, she has up to 29 more chances to try again.
I got one for my wife, who wanted to shoot, but was not comfortable with any number of other guns. (I have a very smooth S&W 66, tuned for competition, and she could handle the trigger, but her groups were
patterns.)
I've shot the PMR-30, but haven't gotten her to try it yet; she CAN rack the slide. I've been very impressed with the gun, so far, but, I've only put about a hundred rounds through it; thus far. No problems of any sort. The word on the 'net is that the new ones are rock solid. It shoots like a LASER. No recoil, but a LOT of noise and flame (often seen as a firey smoke ring!)
Another YouTube video compares performance of the PMR-30 to the FN 5.7, and it does quite well when using comparable (ball) ammo.
If my wife really likes it, I may have to get another one for me... (If I'm away from the house WITH the gun, it's not serving it's intended purpose.)
With regard to it being non-reliable ammo -- I've not heard that as being a problem with .22 WMR. It's not cheap and you seem to get more quality for your money. Pricier types of .22 LR seems to be more reliable, too.