As the foregoing posts suggest, between the two (Models 220 vs 227), for a lot of folks, how a pistol handles and feels in an individual's hand has a lot to do with which one is "best" for that person. I used to own a Model 220 and liked it. Later, I handled a Model 227 and positively loved it. I much prefer the E2 grip and, as it happens, the grip on the 227 is the same as the one on my Model 226 with the E2 grip. Suffice to say that I sold the Model 220 and replaced it with the Model 227. The extra capacity of the double-stack magazine on the Model 227 was just icing on the cake.
In deciding between the two, you really have to handle both to determine which one is the best fit for you.