I might let some other bloke shoot my gun to see what he can do with it, but the bottom line is that I will "mess" with my gun to get it to shoot where I aim since I will be the one shooting it, not Bob, Jonny, Matt or Sally.
Decide beforehand what range and position you expect to most use the gun. You can shoot off a bench at 25 yards to determine the most precise ammunition for your gun, but it makes no sense to make sight adjustments shooting off a bench at 25 yards if you expect to do most of your shooting one-handed at 25 yards or off a rest at 50.
Don't bother to tailor a load to shoot to point of aim either. Find the most precise or powerful load -whatever you're looking for out of your ammunition- and make the gun shoot to the load, not the other way around.