IMO, the Rogers & Spencer was the ultimate 19th Century percussion revolver. It is less prone to cap jams than Remingtons or Colts, and fouls less than the Remingtons. The Ruger Old Army's loading lever is derived from the R&S, as is the anti-fouling ring on the cyclinder face.
Compared with the Colt, Remington, or Ruger, the R&S action is shorter. I.e., the hammer doesn't need to be pulled back as far to cock it. This leads to a shorter lock time which helps accuracy.
The only disadvantage that it has vs. the other percussion wheelguns is the lack of a way to safely carry it with all 6 chambers loaded. You need to carry it hammer down on an empty chamber, because there is no safety notch or pin between chambers.
Mine is a Euroarms in Long Gray.
You can see the raised ring on the front of the cylinder in this pic. It keeps the cylinder base pin from getting fouled.
Since Euroarms was bought by Perdersoli early last year they stopped importing the Rogers & Spencers, but you can probably find one for sale if you look around.