I'm fortunate as my backyard range goes out to 760yds and I basically own a small "valley", so I shoot from slope to slope.
I also do shoot a lot of .22LR practicing, so IF I was distance constrained I'd cut the distance and shrink my tgt size in respect to a deer's kills zone. I like using 6" for my computations, so IF I wanted to practice and all I had was 100yds I'd use a 2.5-3MOA tgt at 100yds to replicate my 250yd shot.
Normal wind isn't much of a player out to 250, so for hold techniques etc. I find the .22LR at 50-100 (or further) to be a great help.
When I competed in Silhouette I had a .22LR built to emulate my match rifle and used scaled animal TGTs and a timer to practice. Back then I belonged to a private range/club and I'd get some odd looks when practicing with my little silhouettes, while most (all?) were shooting from a bench, but it put me in master class. Worked great, so now I use the same type practice for hunting.
More of a precision/NRL22 thing:
Learning a tripod with a Ruger 77/22:
Then, "real rifles" at "real distances", but the concepts were down: