Here is Ernest Langdon with a video after running 50,000 rounds through a Beretta PX4. He broke one part during the test, the cam block, somewhere around the 44,000 round point, shown at about the 2:30 mark in the video.
A forum member elsewhere, who's gone over 100,000 rounds with his Beretta PX4 in .45 Auto, who has communicated directly with Ernest Langdon regarding the issue, attributed the cam block breakage to dropping the slide on an empty chamber. So perhaps it isn't just a 1911 issue. The cam block is a $50ish dollar part, so if you don't mind spending an extra $50 every 40,000ish rounds, drop the slide on an empty chamber all you want.