I'd go with a Sig 229 or 226 - I prefer 9mm, but .40 is a fine choice as well (and with the .229 you can go with both .40 or .357 sig with a barrel swap). The only problem with Sigs - at least for me - is that Sigs tend to multiply. After my first Sig (p229), I traded away my S&Ws, Glock and Ruger - and accumulated another p220, p226, p228 and two p6/p225s.