A good friend of mine was shot through the neck with a .25 during an
altercation at the local juke joint. The bullet went through from the side
without hitting anything vital. He has a small scar on the entrance side,
a very slightly larger scar on the exit side. He didn't know he had been
shot until he hit the guy and saw the gun hit the floor.
I owned a .25 long enough to put 2 boxes of shells through it. I've owned
an IJ TP-22 in .22 for years. Why would anyone choose a .25 over a .22?
Ammo cost alone would make me choose a .22. I own quite
a few large bore handguns, but sometimes you just want something to
drop in your back pocket.
I don't think my buddy would have faired as well if it had been a .22
hollow point that went through his neck. He would have at least heard it.
Obviously, I'd prefer a larger caliber. If you saw my friend (250 lb), you
would too. An eyeball is an awful small target.