Yeah, the .222, The 22PPC, 6mm PPC and the 6.5mm-284 are all renown for exceptional accuracy. Of course, there is the school of thought (which I subscribe to) that says there is no inheirantly accurate calibers. Just some calibers, possibly to the volume dictated, are typically held to lower standards during the manufacturing process. The 22 Hornets and K Hornets are not typically listed among the most accurate cartridges but I have a friend that has a K Hornet which he probably has $1,500 in minus optics that is so accurate it's scary. A good barrel with a proper crown and a tight chamber based on the OAL of your load and carefully made handloads should make for a very accurate rifle regardless of cartridge.