I like a full-sized, all-steel 1911 for the HD role, which works quite well much of the time for CC. This does not mean I believe in one handgun for all circumstances, just that the 1911 is really good for HD, and generally easy enough to conceal. I like the .45 ACP's comparatively mild flash and blast for indoor and low-light environments, though much of the muzzle flash problem has actually been mitigated in recent years, with flash-retardant in the powder of premium defensive/duty loads of cartridges previously known to have bright flash.
Out in the open, I don't mind harsher muzzle blast so much, and can use it to my advantage, adding a bit of shock and awe directed toward an opponent, who will get a much worse dose than I will, being behind the gun, and being not only ready for it, but having trained to tolerate it.
Another reason I like the 1911, is that its grip frame is a nice fit for my large hands, but is narrow enough so my comparatively short-to-medium thumbs and fingers can securely grasp the weapon, and work the controls. I cannot credit the original author of the term, having long forgotten, but I like to use "handsgun" to refer to wide-body pistols with double-column magazines. A handsgun may be OK in the HD role, but I would rather carry and conceal a handgun.
Some folks advocate HD guns that any responsible person in the household can handle and shoot. While I do not disagree with that idea, I see the "household" guns as more like HER guns, which I might use as a back-up plan. Fortunately, we both like medium-frame .357 sixguns.
FWIW, I carry a personally-owned P229R .40 duty pistol at work; I have several authorized choices, all double-column .40 handsguns, but I take my cased 1911 to work with me. (It is on my qual list as an authorized "back-up" pistol.) When out and about on my own time, I tend to carry the 1911 as "primary." I love my .357 revolvers; at least one SP101 snubby is on my person virtually all the time I am not in bed. I may well carry a larger .357 rather than the 1911 when I feel like it, and may carry more than one .357 at a time. I have gone through several "one gun" phases in nearly 30 years of carrying, but am back to believing there is nothing wrong with multiple guns, if one exercises due diligence in maintaining a reasonable skill level with each platform.