look at the pressures of the bottom loads with heavy bullets and that should give you an idea of how high you can go with that model 25. 45 acp +p pressures should be fine in that gun and that pressure is just below the start load for most of those "ruger only" loads in the linebaugh article. h110 is the only powder in those lists that i would not reduce.That entire article is about what can be done with extra strong Ruger actions. I have hundreds of 260-grain .45 Colt HPs at 1200 fps, and at least 200 .454 loaded rounds for my BFR: I need Colt loads close to SAA strength for my S&W.
the article is a reference point for what you are trying to accomplish, not a recommendation for loading at that level.
luck,
murf