No, 5 rounds of 45 LC isn't anything to sneeze at, but I think if I wanted a .45 LC revolver for SD purposes, I would get a more traditional revolver.
A buddy of mine has one and loves it. As he notes, it is an excellent skunk handgun, which is what he uses it for with the .410 shells. It seems that skunks get in and around the out buildings and into places where a long barreled shotgun just won't go very well, but a handgun will.
There are a lot of guns out there in a lot of good calibers, but that does not make those guns ideal for a lot of circumstances. No doubt the Judge can be used for self defense. I just don't see it as being an optimal handgun for self defense purposes, not as compared to other options available to people. Few of us are in situations where we regularly need to transition between .45 LC and .410.
That isn't to say the Judge is a bad or unnecessary gun. I really can't think of a production gun that doesn't have its own place or niche. The Judge is a fun gun in my opinion and there is nothing wrong with fun guns. I just don't see one being part of my SD needs.