Initially I was pretty set on the .22Hornet, now I'm not so sure. I like the Hornet, but honestly my .17HMR fills that role pretty well, and I already load for the .223Rem (but one extra set of dies and new powder isn't a big deal). That being said, the .22Hornet is probably best suited to the somewhat short bbl (this may not be a popular thought, but I wouldn't have a .223Rem./5.56NATO without a barrel of at least 20in.). I don't see any advantage of the .222Rem., as it has a 1:14 twist bbl (the 1:12 on the .223Rem. is bad enough), and I don't already load for it either.