Once upon a time, handguns were usually shot with one hand. Then someone figured out two was better and the Iso stance came about. A bit later a fellow name Weaver had a better idea. Then of course a fellow named Chapman came up with his idea. And on and on it goes.
Bit of truth. If you seriously intend to be able to use a handgun in a combat situation, you'd better be darned able to shoot strong handed, weak handed, two handed, and if you've got a third using that one too.
In addition, you better be able to do it standing, sitting, kneeling, prone, while walking, running, crawling on hands an knees and on your belly.
Their isn't a single "game" out their that even comes close to what you will experince when bullets are coming "at" you. In many cases, if you stand up, assume your favorite stance and two handed grip, while getting a good or even a "flash" sight picture, your enemy will be sitting around his next meal telling his buddies about the idiot who just stood there and let him shoot him.
But what the heck, I've never been a "master" shooter in IDPA, IPSC, Bullseye or any other shooting game. Maybe I should just give up now as I don't have any of the "skills" advanced by the "combat" experts who've never been shot at.