Would I conceal carry a C&B revolver? Sure, I have in the past and still do from time to time. Not in the summer months, I'm a decent sized guy but I can't conceal a five inch barrel 58 Remington without some kind of jacket or workshirt over my regular clothes. So it's fall and winter months at most and really not as often as I would like. Where I work allows me to CC if I wish to do so (actually encouraged at times as my boss likes having a CC permit holder on property), but in that situation I stick to my modern 45 auto...keeping in mind that if one is ever involved in a defensive shooting at a workplace, you don't want to have to explain why you have a blackpowder revolver on you in addition to any other questions that you will have to answer.
When I am not at work, sometimes I still pack shorty with me just because I am very comfortable with a revolver in general, actually prefer revolvers to semi-autos...different discussion...but I'm a good shot with the old single action, I've shot it enough to be confident with it. Some of the discussion on here seems to center on reliability...somebody always brings that up when talking about C&B revolvers, if you use the right components and the right loading technique you'll have no worries about reliability.
A word though, some finish gunsmithing is a good idea with these replica guns, just knowing where to smooth out certain parts and where the typical problems come from is 90% of the battle here. Caps hang on corners and jagged stuff as the cylider turns, cylinders bind (on the remmies) without sufficient lubrication because of a design flaw and a small diameter cylinder pin. If the caps you use give you periodic misfires, its time to try a different brand...I like CCI, I'll get maybe one true misfire in 1000 caps.
As far as loading technique goes, finesse is the key to that lock, a proper seal at both ends of the cylinder gives you a load that will fire when you want it to. I recently fired out two cylinders that I loaded three years ago...no hangfire, just BOOM X 12, just as if I had loaded them that day. BP shooting is an art that requires a little more thought than just stuff in the brass and pull the trigger as fast as you can. In general though I would say that there are valid points on both sides of the CC argument, but you gotta make your own decision.