As i said in my Post #10, 38/45 Clerke, 45 ACP, and 38 Super are my top three favorite semi-auto cartridges to shoot.
But I also load and shoot 40 S&W, 10mm, 357 SIG, 9x19, 380 ACP, 32 ACP, 25 ACP, 22 LR, and 22 Short. (Well, I do not load 22 LR or 22 Short).
So, really, what I'm shooting at the moment is my favorite.
I like shooting 1911's and I have them chambered in 45 ACP, 40 S&W, 357 SIG, 9X19, 38/45 Clerke, 38 Super, and 22 LR.
My 10mm gun is a revolver (S&W 610) but a semi-auto 10mm is probably in my future.