I'd say the real standard these days are the guns with *no* external safety. Talk about intuitive.
But here's the real question. I need sufficient motivation to learn (that means practice...a lot) an entirely new safety configuration. I need a reason to buy an extremely expensive handgun. I need a reason to switch to a round that is difficult to reload and expensive to buy ammo & components. For people like me, there needs to be something that counterbalances those drawbacks. A couple of ounces and a little bit less recoil just don't seem like enough for me. So what else is there?
There have been a lot of guys over the years who have popped themselves thanks to the Glock "safe action" trigger. The Five-seveN also comes with a magazine safety (can be easily disabled) which has saved more than a few lives as well.