Interesting question. The problem that I see with the question and the answers, in my opinion, is that we are assuming defense ONLY in a home scenario; and although this is probably the most likely case in which most of us will have to make the choice of using lethal force or not, it should not be the only consideration. SHTF, post-Katrina N.O. and LA riots comes to mind. If I'm going to own a rifle it needs to be flexible enough (as a system, gun + ammo) to serve me well thru a variety of situations, and I need to train accordingly. With this in mind I'd say that FMJ is out of the question, except for plinking (Bartholomew makes a good point in this regard, I think) and JHP, TAP and SP should be better options for pretty much any situation in which we may find ourselves in. My Golani eats 62 grs HP Brown Bear and 64 grs SP BVAC like is candy, with very little shift in POI out to 200 yards. Just my 2 cents.