1911, though to be fair the CZ75 and SIG P226 are both on the "Next" list. Who knows after that. My series 70 has some serious shortcomings as a Home Defense pistol, (No night sights, no accy rail, hammerbite, 10rnd limit,etc) but a modern 1911 might address those. I will have to own all three pistols to see if familiarity wins out over features. Regardless, the 1911 just always feels right in my hands.
I haven't found the perfect rifle, though my dad's Saiga is always comfy and true, just like my 1911.
(edit) I should add that after 8 years in the Corps, the AR series is real comfy for me. But it remains to be seen if it will be a go to weapon. (First I have to move to a state that will let me have an un-neutered one.)