I haven't shot too many big bore handguns. Defining big bore as any caliber larger than 357mag, here is the list:
Taurus Raging Bull 6" bbl 45Colt
S&W Mod 629 8" bbl 44Mag
1911A1 style gun in 45ACP (can't remember the brand)
My fav is the RB. It's just soooo much fun to shoot and accurate as well. Bowling pins are not safe at 100yds. It's a fine big bore plinker. The 629 was just too long. I liked the 1911, but prefer the RB overall.
Chris