There is no such thing as a 'reliable' 44 Magnum autoloading pistol. The main reason is the huge variance in power level, powders, bullet style, bullet shape, bullet composition, etc. The 44 Magnum was designed for revolvers. In an autoloading pistol like the Desert Eagle, you'll find that many loads will be 100% reliable when the pistol is clean and lubed. The main trick is not to expect or count on 100% reliability in the pistol until you've put a few boxes of your chosen load through the gun without a hitch. Make sure you shoot it left handed, right handed, with a two-handed death-grip and with a single handed limp-wristed hold. Make sure your gun will go bang and cycle every time before you plan on hunting or defending your life with the gun.