Ghost Tracker, let me guess got a boron-carbide plated squirrel infestation going? Yeah had one of those a few weeks back, I hear a .50BMG with API or a 14.7 works wonders .
/asshattery
All silliness, aside, pick what you can shoot the best, but that being said, if someone is worth shooting once, he's worth shooting twice, and I think with a .45 most people will get that second shot in that much faster. A few percent less "one shot stop" rating is worthwhile if it means you can double-tap the guy in the same time it takes to recover from the recoil of a "magnum" cartridge.
/asshattery
All silliness, aside, pick what you can shoot the best, but that being said, if someone is worth shooting once, he's worth shooting twice, and I think with a .45 most people will get that second shot in that much faster. A few percent less "one shot stop" rating is worthwhile if it means you can double-tap the guy in the same time it takes to recover from the recoil of a "magnum" cartridge.