I think max. loaded 45 Super falls in the same catagory as max. loaded 10mm...too much for self defense. Besides, I really don't think todays SD JHPs are built for this kind of velocity. All the velocity in the world doesn't mean crap if the bullet fails. It's kind of like horsepower in a car. If you can't get it to the ground, it's wasted. Todays JHPs are built to expand and penetrate at LOWER velocities to give us lower recoiling guns. Remember the two original 10mm loads? A FMJ and a JHP whos jacket was so thick it rarely, if ever, expanded at all. I think in .45acp, a 200gr. slug at 1050fps or a 230gr. at 950fps (+P velocity) will do anything you could ever need from a SD JHP. In 10mm I like loads that fall bewteen .40 and full-throttle loads. A 155gr. at 1400fps, 165gr. at 1350fps or a 180gr. at 1200fps will work just fine. A 200gr. JHP at 1050fps would be just fine, too. This would be downloaded for a 10mm, but still equals a +P .45acp with better section density.