Lots of good choices depending upon the terrain, cover, hunting method etc. Out of a blind or high hunting stand a good bolt (Ruger, Remmington, Tikka, Savage, etc) in .308, .243, .270 or 30-06 are hard to beat. For stalking, driving, and moving around a small lever gun like the Winny 94, or Marlin 336 in 30-30 are real good, especially with the new Leverevolution ammo! A real good either/or gun is the BLR in .308 or .243. Gives you real nice quick handling almost as good as the smaller Winny/Marlin, plus the added range and accuracy of the bolt gun and the pointy bullets!